Very little information is available on the biology of the Saharan spiny-tailed lizard; however, in general, Uromastyx species are known to be oviparous. The female lays clutches containing between 8 and 20 eggs in burrow systems late in the spring, in the early summer or at the beginning of the dry season (2).
After an incubation period of between eight and ten weeks, the Saharan spiny-tailed lizard eggs hatch. The hatchlings remain within the burrow system for several weeks or months before leaving to create their own burrows (2).
The Saharan spiny-tailed lizard, along with other small Uromastyx species, is thought to reach sexual maturity at two or three years of age. In captivity, wild-caught Saharan spiny-tailed lizards have been known to live for 20 years, and the lifespan estimate for individuals in the wild is 25 years (2).
Adult Saharan spiny-tailed lizards seem to be exclusively herbivorous (2) (7), and feed on a wide range of desert vegetation. However, in captivity young Saharan spiny-tailed lizards are known to eat insects and other invertebrates (2).