Little is known about the biology and life history of the Drakensberg dwarf chameleon. However, like other Bradypodion species, it probably preys on small insects and obtains water by licking dew or raindrops on foliage. During the day, it probably climbs to the top of vegetation to bask in the sun and escape predation, retreating at night into low bushes (4).
Male Bradypodion chameleons are territorial, and their bright colouration becomes most vivid when defending their territories against other males, or when courting females (4). Female Drakensberg dwarf chameleons give birth to live young, instead of laying eggs like most reptiles. However, the pregnant female does not directly supply the embryo with nutrients (known as ‘vivipary’). Instead, the embryo remains within an egg, but develops inside the mother's body (‘ovovivipary’). This is thought to be an adaptive response to the cool temperatures of the mountainous areas this species inhabits (6). Bradypodion chameleons typically give birth to two clutches every year, each containing 5 to 20 young (4), after a gestation period of around three months (2). These chameleons reach sexual maturity after about nine months and live for three to five years (2).