There are very few records of the bushy-tailed opossum, thus little is known about its biology and ecology (5). Like other American opossums, it may be nocturnal and probably feeds on insects, seeds, fruits and eggs (1). Due to their large opposable big toe, it is presumed that the bushy-tailed opossum is arboreal, spending most of its time in the trees (2). However, some specimens have been captured in pitfall trips placed on the ground, showing that it must occasionally use the lower parts of the forest and sometimes move on the ground (5).
Like other marsupials, their unique mode of reproduction sets them apart from other mammals. The young begin development inside a thin-shelled egg within the mother, and are very poorly developed at birth (3). The young is then carried in a pouch on the abdomen of its mother where it suckles her milk and most development takes place. Initially the young remain attached to the teat, but will later begin to crawl about her body. Toward the end of lactation, the young leaves the pouch and follow their mother closely (3)